An introduction to drug synthesis

Part A. Concepts

1. The drug discovery process

2. Drug synthesis

3. Retrosynthesis

4. Cyclic systems in drug synthesis

5. The synthesis of chiral drugs

6. Combinatorial and parallel synthesis

Part B. Applications of drug synthesis in the drug development process

7. Synthesis of lead compounds

8. Analogue synthesis in drug design

9. Synthesis of natural products and their analogues

10. Chemical and process development

11. Synthesis of isotopically labelled compounds

Part C. Design and synthesis of selected antibacterial agents

12. Design and synthesis of tetracyclines

13. Enthromycin and macrolide antibacterial agents

14. Quinolones and fluoroquinolones.