Viruses: the cornerstone of gene therapy
Viruses are living crystals
Viral genomes may be RNA or DNA
Viruses evolved from plasmids
Viruses know how to infect cells
The virus as a gene vehicle
Viruses used in gene therapy
Ashi DeSilva: a promising start
Cells of the immune system
Adenosine deaminase (ADA)
Clinical procedure for ADA gene therapy
The DeSilva clinical trial
Jesse Gelsinger: down to earth
Ornithine transcarbamylase (OTC)
Clinical procedure for OTC gene therapy
The Gelsinger clinical trial
Reducing immune rejection of the vector
Redesigning human anatomy and physiology
Physiological enhancement
The Gelsinger legal trial
X-linked severe combined immunodeficiency (SCID-X1)
Huntington's disease (HD).
